Abdominal drains for ascites

Not Applicable

Recruiting

• Conditions: Ascites; End stage liver disease; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12623001030662
• Lead Sponsor: Southern Adelaide Local Health Network

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-22
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Age >18 years with capacity to consent for treatment
Patient with mild cognitive impairment, at treating doctor and/or PI’s discretion
Refractory ascites
Ascites that is unresponsive to fluid and sodium restriction, and high-dose diuretic treatment (spironolactone 400 mg/day and/or furosemide 160 mg/day) with or without intolerance to diuretics
Ascites that recurs rapidly after LVP (requiring one or more LVP/month).
Considered ineligible to undergo LT and or trans jugular intrahepatic portosystemic shunts (TIPSS)

Exclusion Criteria

Patients with loculated ascites
Patients with large exophytic liver tumours
Patients with chronic abdominal pain
Patients with extensive abdominal wall scars
Patients unlikely to tolerate with abdominal drains at home as judged by the treating medical team
Patients with active spontaneous bacterial peritonitis

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Feasibility and logistics of LTADs within SA health (composite outcome). Feasibility as determined by the uptake of long term abdominal drains by eligible patients assessed by the audit of study records and pre-screening log, and logistics as determined by the ability to insert drains within the hospital setting.[ End of study (24mths)];Number and rate of patient recruitment over 24 months (composite outcome), as determined from the study pre-screening log. [ End of study (24mths)]