EFFECT OF ADJUNCTIVE PLASMA APPLICATION ON NON-SURGICAL PERIODONTAL TREATMENT OF CHRONIC PERIODONTITIS PATIENTS

Not Applicable

Completed

• Conditions: PeriodontitisPeriodontal pocketClinical attachment lossPeriodontal microbiology; Cold plasma; Periodontitis; Periodontal pocket; Anti- infective agents; Biofilm.

• Registration Number: TCTR20180522001
• Lead Sponsor: The Scientific And Technological Research Council

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2016-09-01
• Study Start: 2018-05-22
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

Good general health
Patients having at least 12 natural teeth with minimum of three in each jaw quadrant.
Two sites in each quadrant with a minimum probing depth of 5 mm.

Exclusion Criteria

Smoking
Two sites in each quadrant with a minimum probing depth of 5 mm.
Pregnancy
Lactation
Those who had recieved systemic antibiotics or surgical or non-surgical periodontal treatment within the past 6 months.
Use of long-term administration of anti-inflamatory medications within the past 3 month
Extensive dental prosthetic involvement.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical attachment gain Baseline, 30 days and 3 months. Measured using a manual periodontal probe (milimeters)

Secondary Outcome Measures

Name	Time	Method
Probing Pocket Deptth Baseline, 30 days and 3 months. Measured using a manual periodontal probe (milimeters),Biochemical markers (IL-1b, IL-10, VEGF) Baseline, 30 days and 3 months. Enzym Linked Immunosorbant Assay,Bleeding on probing. Baseline, 30 days and 3 months. Measured using a manual periodontal probe (positive-negative),Microbiologic analyzis Baseline, 30 days and 3 months. Quantative Real Time Polymerase Chain Reaction Analyzis