A Prospective Observational Cohort to Study the Genetics of Obstructive Sleep Apnea and Associated Co-Morbidities

Active, not recruiting

• Conditions: Obstructive Sleep Apnea

• Registration Number: NCT01857427
• Lead Sponsor: Ulysses Magalang MD

Brief Summary

The primary objective of this study is to build a well characterized cohort of patients that will be used to determine the genetic variants associated with obstructive sleep apnea (OSA)and its co-morbidities.

Detailed Description

The purpose of building the cohort is to allow the performance of genome-wide association studies with a large sample of patients that have been well-characterized using standardized procedures.

Study Timeline

• Study Start: 2012-08
• Study First Submitted: 2013-05-10
• Study First Submitted QC: 2013-05-17
• Study First Posted: 2013-05-20
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-19
• Last Update Posted: 2024-04-22
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 5000

Inclusion Criteria

We will recruit subjects who are:

• 18 years of age and older.
• Willing and able to give informed consent

AND any of the following:

• PSG (polysomnogram)requested by a physician based on clinical grounds
• AHI (Apnea-hypopnea index) ≥ 5 episodes per hour based on a prior PSG.

Exclusion Criteria

Incapable of giving informed consent

• Under the age of 18

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sleep Questionnaire	upon enrollment	Responses to sleep questionnaire

Trial Locations

Locations (1)

Suite 2600, Martha Morehouse Medical Pavilion; 🇺🇸 Columbus, Ohio, United States