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Incyte

🇺🇸United States
Ownership
-
Employees
2.5K
Market Cap
$12.6B
Website
Introduction

Incyte Corp. is a biopharmaceutical company, which engages in the discovery, development, and commercialization of proprietary therapeutics. It focuses on hematology and oncology, and inflammation and autoimmunity therapeutic areas. The company was founded in April 1991 and is headquartered in Wilmington, DE.

Clinical Trials

620

Active:351
Completed:136

Trial Phases

5 Phases

Phase 1:420
Phase 2:100
Phase 3:66
+2 more phases

Drug Approvals

16

CANADA:6
FDA:4

Drug Approvals

ZYNYZ

Approval Date
Nov 10, 2023
FDA

OPZELURA

Approval Date
Sep 20, 2023
FDA

PEMAZYRE

Approval Date
Jun 1, 2023
FDA

JAKAFI

Approval Date
Jan 31, 2023
FDA

Clinical Trials

Distribution across different clinical trial phases (590 trials with phase data)• Click on a phase to view related trials

Phase 1
420 (71.2%)
Phase 2
100 (16.9%)
Phase 3
66 (11.2%)
Not Applicable
3 (0.5%)
Phase 4
1 (0.2%)

A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy

Not Applicable
Not yet recruiting
Conditions
Chronic Graft-versus-host-disease
Interventions
Drug: Best available Treatment (BAT)
First Posted Date
2025-08-15
Last Posted Date
2025-08-15
Lead Sponsor
Incyte Corporation
Target Recruit Count
60
Registration Number
NCT07124078

Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders

Not Applicable
Not yet recruiting
Conditions
Immune Thrombocytopenia
Interventions
Drug: INCA000585
First Posted Date
2025-08-05
Last Posted Date
2025-08-11
Lead Sponsor
Incyte Corporation
Target Recruit Count
56
Registration Number
NCT07104565

Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa

Not Applicable
Not yet recruiting
Conditions
Hidradenitis Suppurativa
Interventions
First Posted Date
2025-07-03
Last Posted Date
2025-07-11
Lead Sponsor
Incyte Corporation
Target Recruit Count
24
Registration Number
NCT07049575

Study to Assess the Safety, Tolerability, and Pharmacokinetics of INCB000631 When Administered Orally to Healthy Adult Participants

Phase 1
Recruiting
Conditions
Healthy Participants
Interventions
Drug: Placebo
First Posted Date
2025-06-26
Last Posted Date
2025-08-17
Lead Sponsor
Incyte Corporation
Target Recruit Count
48
Registration Number
NCT07039929
Locations
🇺🇸

Celerion, Inc, Lincoln, Nebraska, United States

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Phase 2
Recruiting
Conditions
Ovarian Cancer
Interventions
First Posted Date
2025-06-17
Last Posted Date
2025-08-15
Lead Sponsor
Incyte Corporation
Target Recruit Count
160
Registration Number
NCT07023627
Locations
🇺🇸

Usa Health Mitchell Cancer Institute, Mobile, Alabama, United States

🇺🇸

Uams Winthrop P Rockefeller Cancer Institute, Little Rock, Arkansas, United States

🇺🇸

University of California, Los Angeles Medical Center, Los Angeles, California, United States

and more 70 locations
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News

Vitiligo Treatment Pipeline Shows Promise with JAK Inhibitors and Novel Immunotherapies in Phase 3 Trials

Over 18 companies are actively developing 20+ pipeline therapies for vitiligo treatment, with JAK inhibitors leading the charge in late-stage clinical trials.

Incyte Reports Strong Q2 2025 Results with Jakafi Growth and New Drug Approvals

Incyte reported strong second quarter 2025 financial results with Jakafi net revenues of $764 million, representing 8% year-over-year growth driven by increased demand across all indications.

MacroGenics Secures $70 Million in ZYNYZ Royalty Deal, Extends Cash Runway Through 2027

MacroGenics received a $70 million upfront payment from Sagard Healthcare Partners through a royalty purchase agreement for ZYNYZ, a PD-1 inhibitor approved for anal canal carcinoma and Merkel cell carcinoma.

ASCO 2025 Showcases Advances in Myelofibrosis Treatment with Novel JAK Inhibitors and Personalized Approaches

The 2025 ASCO Annual Meeting highlighted significant progress in myelofibrosis treatment, featuring novel JAK inhibitors like momelotinib and pacritinib that offer alternatives to standard ruxolitinib therapy.

Essential Thrombocythemia Market Set for Significant Growth as Novel Therapies Enter Pipeline

Essential thrombocythemia affects approximately 167,000 individuals in the US as of 2024, with 75% of cases linked to JAK2 gene mutations and only one approved therapy currently available in Europe.

Researchers Unveil New Strategies to Harness Tumor Microenvironment for Enhanced Cancer Immunotherapy

Researchers at the 2025 ASCO Annual Meeting revealed how the tumor microenvironment's complex balance of pro-tumor and anti-tumor immune forces can be manipulated to improve immunotherapy responses.

Global GVHD Clinical Trials Review Reveals Key Trends and Strategic Opportunities for 2025

A comprehensive analysis of the global Graft Versus Host Disease clinical trial landscape shows significant activity across G7 and E7 countries, offering strategic insights for pharmaceutical companies.

Promising Pipeline for Mantle Cell Lymphoma Treatment: 22+ Therapies Under Development by 20+ Companies

DelveInsight's latest report reveals a robust pipeline with 20+ companies developing 22+ therapies for mantle cell lymphoma, highlighting significant advancement in treatment options for this rare blood cancer.

Sun Pharma's Leqselvi Advances Toward Launch After Favorable US Court Ruling

Sun Pharmaceutical Industries has gained significant legal leverage after a US Court of Appeals vacated a preliminary injunction against its alopecia areata treatment Leqselvi, potentially enabling commercialization despite ongoing litigation with Incyte.

U.S. Court Ruling Clears Path for Sun Pharma's Alopecia Drug Leqselvi Launch

The U.S. Court of Appeals for the Federal Circuit has vacated a preliminary injunction against Sun Pharma, allowing the company to proceed with launching Leqselvi (deuruxolitinib) for alopecia areata in the American market.

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