Investigating Treatment and Information Processing in Olfactory Reference Syndrome: A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Yale-Brown Obsessive Compulsive Scale Modified for olfactory reference syndrome (ORS-YBOCS)
研究概览
简要总结
The primary aim of the study is to test the feasibility and efficacy of, a manual based, Internet-delivered, cognitive behaviour therapy (CBT) for patients with Olfactory Reference Syndrome (ORS) who live in Sweden. The secondary aim is to investigate smell sensitivity and body odor in these ORS-patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Primary diagnosis of ORS
- •Outpatients
- •Male or female
- •Signed informed consent
- •Have regular access to a computer with Internet access and skills to use the web
排除标准
- •Not able to read or understand the basics of the ICBT self-help material
- •Psychotropic medication changes within two months prior to treatment
- •Completed CBT for ORS within last 12 months
- •Ongoing substance dependence or misuse
- •Lifetime bipolar disorder or psychosis
- •Suicidal ideation
- •Axis II diagnosis that could jeopardize treatment participation
- •Serious physical illness that will be an obstacle in ICBT
- •Other ongoing psychological treatments that could affect ORS symptoms
- •Epilepsia
结局指标
主要结局
Yale-Brown Obsessive Compulsive Scale Modified for olfactory reference syndrome (ORS-YBOCS)
时间窗: Change from baseline (week 0) to post-treatment (week 10).
The instrument is a 12-item clinician-administered scale rating the severity of ORS symptoms during the past week. Each item is scored along a Likert scale ranging from 0 (least extreme) to 4 (most extreme), with higher total scores indicating more severe ORS symptoms (range 0-48).
次要结局
- The Montgomery Åsberg Depression Rating Scale - self report (MADRS-S)(Change from baseline (week 0) to post-treatment (week 10).)
- Yale-Brown Obsessive Compulsive Scale Modified for olfactory reference syndrome - Self Report (ORS-YBOCS-SR)(Change from baseline (week 0) to post-treatment (week 10).)
研究者
Volen Ivanov
Principal Investigator
Karolinska Institutet