Measurement of calcium concentrations in serum and a single hair shaft

Not Applicable

• Conditions: Healthy men and women who are younger than 40 years in age.

• Registration Number: JPRN-UMIN000004977
• Lead Sponsor: The SHIMA Institution for Quantum Medicine

Brief Summary

Elemental concentrations in hair and dried serum from 5 female and 5 male healthy subjects under continuous intake of Calcium (Ca) capsule (900 mg daily) for 14 days have been observed by X-ray fluorescence analysis with the definition of relative concentration free from specimen thickness. The dried serum samples from the10 test subjects with Ca supplementation for 2 weeks showed the same relative concentration for each of elements such as Ca, Cl, K, S and P under the renal control by parathyroid hormone (PTH). X-ray fluorescence analysis of these 10 test subjects showed that 8 out of 10 had DA type (one of hair Ca metabolism types with lower hair Ca concentration than normal range of hair Ca), 2 out of 10 had LD type (long-term Ca channel gating with Ca deficiency) and LD type suspected. Elements in the dried serum were all normalized with Ca intake for 2 weeks, although there were some test subjects whose elements in the hair were not normalized. Hair element concentrations have also been measured in 50 randomly-selected females aged between 30s and 70s. The results showed that each element has two separate levels, with a relatively higher and lower concentration of elements. The elements in growing hair in a steady state must depend on the inflow of elements into the hair matrix cells on hair root from serum. Using this principle, the two concentration levels can be attributed to gating and closing of the ion channels in cell membrane and are proportional to the standard concentrations of the dried serum. By analyzing elements in the hair and dried serum of 5 normal men and women by x-ray fluorescence analysis under continuous intake of Ca for 2 weeks, Ca metabolism type can be detected and it may be possible to reduce cancer risk by taking Ca every day in a person who shows LD type (long-term Ca channel gating with Ca deficiency).

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-01-30
• Study Completion: 2011-03-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Not provided

Exclusion Criteria

1 Men and women who feel unhealthy in a daily life. 2 Men and women who are treated by medical doctors. 3 Men and women who have heart diseases.

Study & Design

• Study Type: Interventional
• Study Design: Not specified