Investigation of the Effect of Calisthenic Exercise Training Combined With Aerobic Exercise on Exercise Tolerance, Physical Fitness and Plasma Lipid Profile in Patients With Dyslipidemia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 39
- 试验地点
- 1
- 主要终点
- Exercise Capacity
研究概览
简要总结
Dyslipidemia is expressed as the serum concentration of lipid molecules with different structures outside the normal level. Deviation of serum lipid level from normal is accepted as the primary or most important factor in various cardiac and metabolic diseases, especially atherosclerosis. Dyslipidemia-related cardiovascular structure change is accepted as an important public health problem worldwide, and it is stated that the combined use of medical treatment, changes in diet and physical activity/structured exercise programs in the treatment of dyslipidemia is important in the success of treatment.
详细描述
Lipid profile disorders (especially high total blood cholesterol level) are a major problem worldwide, and accepted as a important public health problem. It has been reported that approximately one out of every three people worldwide has been exposed to dyslipidemia risk factors. Prevalence studies showed that lipid profile disorders vary between 6.9% and 43.6% worldwide. Today, ischemic heart and central nervous system diseases are the most important causes of mortality and morbidity in adult population, globally. Especially, it is accepted that lipid profile disorders are the leading risk factors causing ischemic heart diseases.
Prevalence varies according to regions, lifestyle habits and individual factors, because of lipid profile disorders are caused by many different genetic and environmental factors. Apart from individual factors, there are other factors that lipid weight in diet, nutrient deficiencies which balancing lipid metabolism, physical activity level and inactivity, other comorbid diseases, and medical treatments change lipid metabolism in individuals and lead to deterioration in lipid profile. Especially lifestyle habits affect lipid metabolism most easily and they are the most easily modifiable factors.
It is recommended to apply a multi-dimensional approach when treating lipid profile disorders. It is recommended that, to include diet counseling and exercise therapy in these approaches. Exercise therapy is especially recognized as an important treatment option for the control and treatment of obesity, hypertension, hyperglycemia and metabolic syndrome symptoms that may accompany dyslipidemia.
It has been reported that aerobic exercise programs increase patients' quality of life and functionality which applied to dyslipidemia patients, but there is lack of information available in literature about the effects of calisthenic exercises in patients with dyslipidemia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
盲法说明
Patients and his/her caregivers will allocate in study via computer based randomisation, and will not know about his/her and also other participants group in study.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Screening by the internal medicine clinic with the diagnosis of dyslipidemia
- •Being between 18 to 65 years old
- •Volunteering to participate in the research
排除标准
- •Having any cardiac disease
- •Having a co-existing psychiatric illness (like schizophrenia, bipolar disorder, etc.)
- •Being infected with COVID-19 in the last 3 months
- •Having any neurological problems that may affect cooperation
- •Having pulmonary or orthopedic problem that may affect functional capacity
结局指标
主要结局
Exercise Capacity
时间窗: Second Day
Cardiopulmonary exercise capacity will assess as primary outcome measure, via cardiopulmonary exercise test (CPET).
次要结局
- Blood Sugar Concentration Assessment(First Day)
- C-reactive Protein Concentration Assessment(First Day)
- Timed Up-and-Go Test(First Day)
- Peripheral Muscle Strength Assessment(First Day)
- Flexibility Assessment(First Day)
- Blood Lipids Concentration Assessment(First Day)
- Apolipoprotein A1 Concentration Assessment(First Day)
- Sit-to-Stand Test(First Day)
- Hand-Grip Strength Assessment(First Day)
研究者
Furkan Özdemir
Lecturer
Çankırı Karatekin University