Effect of vitamin E supplementation on nitrosative and oxidative stress, serum zinc and metabolic status in type 2 diabetics
Not Applicable
- Conditions
- diabetes mellitus.Non-insulin-dependent diabetes mellitus
- Registration Number
- IRCT138904263664N2
- Lead Sponsor
- Vice-chancellor for research, Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
volunteer for participating in the study; diagnosis of diabetes at least 1 year prior to our examination; patients under treatment only with oral hypoglycemic agents at least for 6 months; BMI=35; 30-60 years old. Exclusion criteria: pregnancy and lactating; liver, renal, heart, thyroid and inflammation disease; patients who are under treated with insulin, hypolipidemic and diuretic drugs, and who use fish oil or garlic capsules and under treated with hormone; smoking; any change in dose of lowering blood glucose drugs which used by patients during the intervention; taking antioxidant supplements at least 3 months before the beginning of study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Metabolic status. Timepoint: before of intervention and 8 weeks after intervention. Method of measurement: blood sampling and analysing with related tests.;Nitrosative stress. Timepoint: before of intervention and 8 weeks after intervention. Method of measurement: blood sampling and analysing with griess.;Oxidative stress. Timepoint: before of intervention and 8 weeks after intervention. Method of measurement: blood sampling and analysing with spectrophotometry.;Level of serum zinc. Timepoint: before of intervention and 8 weeks after intervention. Method of measurement: blood sampling and analysing with spectrophotometry.
- Secondary Outcome Measures
Name Time Method