Visualisation of coronary arteries for the analysis of premature atherosclerosis in patients with adult-onset growth hormone deficiency
- Conditions
- growth hormone deficiency1001108210021112
- Registration Number
- NL-OMON30113
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 30
1. Biochemically proven GH deficiency
2. Age between 35 and 60 years
3. GH deficient within half a year of neurosurgical procedure or GH deficient at least 5 years
4. Optimal substitution of other hormones
1. BMI >30
2. Positive history of myocardial or valve or coronary disease or symptoms that suggest coronary disease (chest pain in rest or during exercise)
3. Rhythm disturbances
4. Moderate or severe pulmonary disease
5. Impairment in renal function (Creatinin clearance < 60 ml/min)
6. Positive family history of primary dyslipidemia
7. Positive family history from premature cardiovascular disease
8. Positive family history of diabetes type II
9. Allergy for contrast
10. Claustrophobia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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