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The Safety and Effectiveness of (+)-Calanolide A in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

Phase 1
Conditions
HIV Infections
Registration Number
NCT00005120
Lead Sponsor
Sarawak MediChem Pharmaceuticals
Brief Summary

The purpose of this study is to see if it is safe and effective to give calanolide A to HIV-infected adults who have not used anti-HIV drugs in the past.

Detailed Description

Patients are randomized to receive (+)-calanolide A or placebo for 21 days. All patients may elect to receive an open-label, 3-month course of approved retroviral therapy (up to triple-drug therapy) to be selected by, and administered under the care of, the patients' physicians. If the patient has no insurance coverage or does not wish to utilize his/her insurance for anti-HIV medications, Sarawak MediChem Pharmaceuticals will provide these medications at no charge for up to 3 months.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
16
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (6)

Univ of Texas Med Branch

🇺🇸

Galveston, Texas, United States

South Florida Bioavailability Clinic

🇺🇸

Miami, Florida, United States

Chicago Ctr for Clinical Research

🇺🇸

Chicago, Illinois, United States

The CORE Ctr

🇺🇸

Chicago, Illinois, United States

Burnside Clinic

🇺🇸

Columbia, South Carolina, United States

Anderson Clinical Research

🇺🇸

Pittsburgh, Pennsylvania, United States

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