Successful aging in the information society- Sensory modality as a key to understanding selective attention in aging and dementia.

Completed

Conditions: prodromal phase of Alzheimer's disease
Alzheimer's disease
dementia

Registration Number: NL-OMON43842

Lead Sponsor: niversiteit Maastricht

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 30

Inclusion Criteria

- Diagnosis of MCI based on the latest research criteria (clinical assessment at the memory clinic): presence of at least a memory impairment, memory complaints expressed by the patient or informant, and no problems in daily life functioning
- Presence of CSF biomarkers or medial temporal lobe atrophy (medial temporal lobe atrophy scale (MTA) score > 3,(Scheltens et al., 1992), indicative of an underlying AD-pathology
- 60- 80 years of age
- Mini Mental State Examination (MMSE) score of *23, ensuring inclusion of only mentally competent, mild MCI patients, able to understand the purpose and instructions of the study and to give informed consent

Exclusion Criteria

- Any persisting major medical conditions (for example cancer or heart disease)
- Presence of psychiatric or neurological disorders (e.g.: major depression, bipolar disorder, psychotic disorders; epilepsy, multiple sclerosis or Parkinson*s Disease)
- History of brain surgery, major brain trauma, or infection
- Significant reductions of visual acuity (after optical correction)
- Significantly reduced hearing ability (interfering with the understanding of stimuli presented during the study)
- Involvement in any other cognitive or pharmaceutical intervention, aiming to improve cognition for the duration of the study

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- Performance (reaction times and accuracy) on a selective attention tasks<br /><br>under different conditions of attention and distraction. </p><br>

Secondary Outcome Measures