Persistence of Rabies Antibody 1-5 Years After the Post-exposure Prophylaxis With Vero Cell Antirabies Vaccine and Antibody Response to a Single Booster Dose
Phase 4
- Conditions
- Rabies
- Interventions
- Biological: Rabies vaccine, manufactured by ChengDa
- Registration Number
- NCT01173302
- Lead Sponsor
- Peking University People's Hospital
- Brief Summary
This study is to investigate the persistence of rabies Chinese manufactured antibody 1-5 years after the post-exposure prophylaxis with vero cell antirabies vaccine and antibody response to a single booster dose. A total of 160 subjects would be enrolled. These subjects were all administered ChengDa antirabies vaccine from 2005 to 2009. After informed consent is obtained, these subjects would be tested for their antirabies antibody titer and given a single booster dose. Seven and 14 days later, the investigators would re-evaluate the antibody titer.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 160
Inclusion Criteria
- 20 to 60 years old
- Healthy
- Given ChengDa rabies vaccine
- Good compliance
- Obtained informed consent
Exclusion Criteria
- Other than inclusion criteria
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Post vaccination Rabies vaccine, manufactured by ChengDa All the subjects had been vaccinated with antirabies vaccine.
- Primary Outcome Measures
Name Time Method Rabies antibody titer 6 months We test the antirabies antibody titer before and after the single booster dose
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Peking University People's Hospital
🇨🇳Beijing, Beijing, China