NL-OMON32507
Not yet recruiting
Not Applicable
The difference in fractional cholesterol absorption between subjects with high versus low plasma campesterol levels - DAHLIA-2
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- mild hypercholesterolaemia
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 13
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Healthy male and female subjects, aged 18\-65 years old, with an LDL\-cholesterol concentration between 3\.0 and 5\.0 mmol/l, who participated in the Dahlia\-1 study and belong to the 6 subjects with the highest or to the 6 subjects with the lowest plasma campesterol levels respectively. One subject with the subsequently highest campesterol levels will be asked to undergo a cholesterolabsorption measurement as well, in order for us to test the quantification of cholesterol isotopes by our laboratory.
Exclusion Criteria
- •Excluded are persons with a genetic hyperlipoproteinemia like familial hypercholesterolemia, LPL\-deficiency, familial dysbeta lipoproteinemia and familial hypertriglyceridemia. Also people with diabetes mellitus, severe hypertriglyceridemia, uncontrolled hypertension or history of arterial disease including unstable angina, myocardial infarction, recent transient ischaemic attacks or a cerebro\-vascular accident, will be excluded.
Outcomes
Primary Outcomes
Not specified
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