NL-OMON34258
Not yet recruiting
Not Applicable
Validation of cholesterol absorption as measured by the dual isotope method - DAHLIA-2B
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- mild hypercholesterolemia
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 7
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Healthy male and female subjects, aged 18\-65 years, with an LDL\-cholesterol concentration between 3\.0 and 5\.0 mmol/l, who participated in the Dahlia\-2a study and who do not use any cholesterol\-lowering medication.
Exclusion Criteria
- •Excluded are persons with a genetic hyperlipoproteinemia like familial hypercholesterolemia, LPL\-deficiency, familial dysbeta lipoproteinemia and familial hypertriglyceridemia. Also people with diabetes mellitus, severe hypertriglyceridemia, uncontrolled hypertension or history of arterial disease including unstable angina, myocardial infarction, recent transient ischaemic attacks or a cerebro\-vascular accidents, will be excluded.
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Phase 4
Plaque REgression with Cholesterol absorption Inhibitor or Synthesis inhibitor Evaluated by IntraVascular UltraSoundpatients aged 30-85 years who were undergoing percutaneous coronary intervention (PCI, elective or emergency) with >=1 significant stenosis >=75% and >=1 untouched nonculprit lesion of <=50% stenosis that could be imaged by intravascular ultrasound, and either LDL-C >=100 mg/dl.JPRN-UMIN000002959Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University300
Completed
Not Applicable
The study about the effects of cholesterol absorption inhibition on coronary artery plaque in patients treated with PCIcoronary artery diseasesJPRN-UMIN000026581Kurume University Medical Center50
Completed
Phase 4
Therapeutic effects of cholesterol absorption inhibitor on renal function in patients with chronic kidney diseaseChronic kidney disease HypercholesterolemiaJPRN-UMIN000002528Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine50
Recruiting
Not Applicable
Serum levels of Cholesterol synthesis/absorption markers in subjects of various diseases.ormal subjects, Diabetes, Hyperlipidemia, Essential hypertension, Metabolic syndromeJPRN-UMIN000004946Department of Metabolic Medicine, Faculty of life sciences, Kumamoto University600
Not yet recruiting
Not Applicable
The difference in fractional cholesterol absorption between subjects with high versus low plasma campesterol levelsmild hypercholesterolaemiaslightly elevated cholesterol10013317NL-OMON32507Academisch Medisch Centrum13