To compare and evaluate the antimicrobial efficacy (in terms of bacterial load reduction) of combination of ozone oil with Chitosan Nano-particle and Double Antibiotic Paste as intracanal medicament in teeth requiring retreatment of previously done root canal therapy.
- Conditions
- Health Condition 1: - Health Condition 2: K045- Chronic apical periodontitisHealth Condition 3: K045- Chronic apical periodontitisHealth Condition 4: K045- Chronic apical periodontitisHealth Condition 5: K045- Chronic apical periodontitisHealth Condition 6: K04- Diseases of pulp and periapical tissues
- Registration Number
- CTRI/2023/02/049482
- Lead Sponsor
- Dr Harshit Mavani
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 32
Systemically healthy patients, i.e., Class I patients according to American Society of Anaesthesiology [ASA] classification having multirooted teeth diagnosed with post treatment apical periodontitis will be included.
Teeth indicated for endodontic retreatment will be included.
A written informed consent will be taken from all the patients and only those patients ready to sign the consent form will be included in the study.
Patients who received antibiotic therapy within the previous 3 months
Teeth with vertical root fracture
Teeth with periodontal pockets deeper than 4 mm
Teeth in which prosthesis could not be removed.
Teeth with severe crown destruction
Teeth with separated instrument
Patients with known allergy to Shrimps/Chitosan
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The result of this study will help us to know about the antibacterial efficacy of combination of ozone oil with chitosan nanoparticle as intracanal medicamentTimepoint: First sample will be taken at baseline. Second sample will be taken after a week (7 days)
- Secondary Outcome Measures
Name Time Method To know which has better antibacterial activity between combination of ozone oil with chitosan nanoparticle and double antibiotic pasteTimepoint: 7 days