A CLINICAL STUDY TO ASSESS THE EFFECTIVENESS AND SYMPTOMATOLOGY OF COMMONLY INDICATED HOMOEOPATHIC REMEDIES IN THE TREATMENT OF AUTOIMMUNE HYPOTHYROIDISM
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1.To assess the effectiveness of commonly indicated Homoeopathic remedies in the treatment of Autoimmune hypothyroidism
研究概览
简要总结
| Hypothyroidism may be defined as a deficient thyroidal production of thyroidal hormones. It could either be due to problems in the thyroid gland itself (primary hypothyroidism) or may be caused by an insufficient stimulation of the thyroid gland due to factors interfering with pituitary TSH release (secondary hypothyroidism) or indirectly by diminishing hypothalamic TRH release (tertiary hypothyroidism). Secondary and tertiary hypothyroidism are together known as central hypothyroidism and are rare. Whereas Primary hypothyroidism is very prevalent worldwide |
The prevalence of hypothyroidism in India was found to be 11% with higher rates in women as compared to men
Overt primary hypothyroidism is diagnosed biochemically with a serum thyroid stimulating hormone (TSH) concentration above the reference range and low free T4 If the TSH is raised but free T4 is in the normal range, then this is referred to as subclinical hypothyroidism
The commonest cause of primary hypothyroidism is autoimmune thyroiditis accounting for 90 % of all cases. Hashimoto’s thyroiditis (70%) and Graves’ disease (20%) are the most common types of autoimmune thyroid diseases
Hashimoto’s thyroiditis diagnosis depends on the level of circulating antibodies mainly Anti-Thyroid Peroxidase antibody which contributes for about 90% sensitivity to diagnose autoimmune thyroiditis
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •Subjects with autoimmune hypothyroidism who fulfill the diagnostic criteria in the age group of 18– 65 years.
- •Subjects who are willing to take part in the study and sign the written informed consent.
排除标准
- •Subjects with Grave’s disease.
- •Subjects with Thyroid malignancy or any other malignancy Pregnant and lactating women.
结局指标
主要结局
1.To assess the effectiveness of commonly indicated Homoeopathic remedies in the treatment of Autoimmune hypothyroidism
时间窗: 24 months
次要结局
- 2.To understand the symptomatology of commonly indicated Homoeopathic remedies in the treatment of Autoimmune hypothyroidism(24 months)
