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临床试验/CTRI/2017/09/009868
CTRI/2017/09/009868招募中2 期

Clinical study in management of Primary Hypothyroidism with Gomutra Haritaki with special reference to Kaphaja Pandu

Ritu Sheoran1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2017年1月1日最近更新:

试验速览

阶段
2 期
状态
招募中
发起方
入组人数
30
试验地点
1
主要终点
improvement in presenting complaints of weight gain,constipation,pallor, decreased mental and physical activities,hoarseness of voice and others

研究概览

简要总结

Hypothyroidismis one of the most common functional disorders of the thyroid gland. A state of Hypothyroidism can be dueto primary disease of the thyroid gland itself or lack of pituitary TSH[Thyroid Stimulating Hormone].A keen insight to the pathogenesis ofhypothyroidism according to the principles of Ayurveda, we find that it is basically caused due to dysfunctioningof the ‘Agni (dhatvagni)’.If we compare various symptoms of hypothyroidismand Kaphaja Pandu, we find that manysigns and symptoms can be correlated with each other, for example, paleness and dryness of skin, hair fall,hoarseness of voice, cold intolerance, modest weight gain, reduced appetite,lethargy, somnolence, puffy face with oedematous eyelids, nonpitting pretibial oedemaetc. So hypothyroidism is similar to Panduespecially to ‘Kaphaja Pandu’. Gomutra and Haritaki arehaving Katu-Tikta-Kashaya Rasapredominance and Ushna Veeryawhich actas Kapha Hara and may help tobreakdown the pathology of Kaphaja Panduand hypothyroidism. For this purpose, “GOMUTRA HARITAKI†mentioned by Aacharya Charak in Pandu Chikitsa is selected.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Patients of either sex with age group 20-60 years.
  • 2.Patients who are diagnosed as primary hypothyroidism.

排除标准

  • 1.Patients suffering from systemic diseases like cardiac problems, diabetes, carcinomas etc.
  • 2.Patients suffering from congenital hypothyroidism and secondary hypothyroidism.
  • 3.Pregnant women,patients with hyperthyroidism will be excluded.

结局指标

主要结局

improvement in presenting complaints of weight gain,constipation,pallor, decreased mental and physical activities,hoarseness of voice and others

时间窗: 90 days

次要结局

  • improvement in thyroid function test values(90 days)

研究者

发起方
Ritu Sheoran
申办方类型
Other [self]

研究点 (1)

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