HOMOEOPATHIC MEDICINES IN TREATMENT OF AUTOIMMUNE HYPOTHYROIDISM

Not yet recruiting

• Conditions: Autoimmune thyroiditis,

• Registration Number: CTRI/2025/06/089707

Brief Summary

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|Hypothyroidism may be defined as a deficient thyroidal production of thyroidal hormones. It could either be due to problems in the thyroid gland itself (primary hypothyroidism) or may be caused by an insufficient stimulation of the thyroid gland due to factors interfering with pituitary TSH release (secondary hypothyroidism) or indirectly by diminishing hypothalamic TRH release (tertiary hypothyroidism). Secondary and tertiary hypothyroidism are together known as central hypothyroidism and are rare. Whereas Primary hypothyroidism is very prevalent worldwide

The prevalence of hypothyroidism in India was found to be 11% with higher rates in women as compared to men

Overt primary hypothyroidism is diagnosed biochemically with a serum thyroid stimulating hormone (TSH) concentration above the reference range and low free T4 If the TSH is raised but free T4 is in the normal range, then this is referred to as subclinical hypothyroidism

The commonest cause of primary hypothyroidism is autoimmune thyroiditis accounting for 90 % of all cases. Hashimoto’s thyroiditis (70%) and Graves’ disease (20%) are the most common types of autoimmune thyroid diseases

Hashimoto’s thyroiditis diagnosis depends on the level of circulating antibodies mainly Anti-Thyroid Peroxidase antibody which contributes for about 90% sensitivity to diagnose autoimmune thyroiditis

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-06-26
• Study Start: 2025-10-07

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Subjects with autoimmune hypothyroidism who fulfill the diagnostic criteria in the age group of 18– 65 years.
• Subjects who are willing to take part in the study and sign the written informed consent.

Exclusion Criteria

• Subjects with Grave’s disease.
• Subjects with Thyroid malignancy or any other malignancy Pregnant and lactating women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.To assess the effectiveness of commonly indicated Homoeopathic remedies in the treatment of Autoimmune hypothyroidism	24 months

Secondary Outcome Measures

Name	Time	Method
2.To understand the symptomatology of commonly indicated Homoeopathic remedies in the treatment of Autoimmune hypothyroidism	24 months

Trial Locations

Locations (1)

Government Homoeopathic medical college and hospital Banglore; 🇮🇳 Bangalore, KARNATAKA, India

Government Homoeopathic medical college and hospital Banglore

🇮🇳Bangalore, KARNATAKA, India

Dr Rajeshwari Principal

Principal investigator

08023359413

ghmchprincipal@gmail.com