跳至主要内容
临床试验/NCT01621074
NCT01621074已完成不适用

Influence of Sodium Bicarbonate on Time-to-exhaustion at Critical Power in Endurance Athletes

University of Zurich1 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2011年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
12
试验地点
1
主要终点
Time-to-exhaustion

研究概览

简要总结

During endurance exercise in the heavy and severe intensity domains, the rate at which metabolites that have been associated with the fatigue process (e.g. Pi, ADP, H, and extracellular K) accumulate increases. possibly leading to exercise cessation. Sodium bicarbonate, as a nutritional supplement, has gained attention over the past decades, because it might delay of offset fatigue. To date, there is a controversial discussion about which delivery mode (amount and frequency) might be best in optimizing endurance performance. Since the high ion load consequent to multiple ingestions might increase plasma volume, and consequently decrease bicarbonate concentrations, single acute ingestion could be more beneficial. However, in multi-day competitions or tournaments it might be necessary to use the supplement on a daily basis. Here, the investigators aim at investigating the effects of single dose or multiple dose (on five consecutive days) administration of bicarbonate vs. placebo increases endurance performance and acid-base homeostasis in trained male endurance athletes.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
Male
接受健康志愿者
否

入选标准

  • •no cold or temperature at beginning or during the study
  • •between 18 and 45 years of age
  • •active in endurance sports (3 to 5 times per week a moderate to hart training)
  • •non-smoker
  • •no known cardiovascular or orthopedic problems
  • •no known limitations of kidney function
  • •no bearer of a cardiac pacemaker
  • •no medications with direct influence on the measurements. The whole intake of medicaments has to be declared in the health questionnaire by the participant.
  • •requirements of the health questionnaire fulfilled

排除标准

  • •male and age under 18 or over 45 years
  • •cold or temperature at the beginning or during the study
  • •untrained (less than 3 moderate trainings per week)
  • •cardiovascular or orthopedic problems
  • •limitations of the kidney function
  • •bearer of a cardiac pacemaker
  • •medication with direct influence on the measurements. The whole intake of medicaments has to be declared in the health questionnaire by the participant.
  • •requirements of the health questionnaire not fulfilled

研究组 & 干预措施

Placebo

Placebo Comparator

干预措施: Placebo (Dietary Supplement)

Sodium bicarbonate

Active Comparator

干预措施: Sodium bicarbonate (Dietary Supplement)

结局指标

主要结局

Time-to-exhaustion

时间窗: 5 weeks

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验