Detection of circulating epithelial tumour cells (DETECT)

Completed

• Conditions: Metastatic breast cancer; Cancer; Malignant neoplasm of breast

• Registration Number: ISRCTN59722891
• Lead Sponsor: niversity of Tuebingen (Germany)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-05-04
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 254

Inclusion Criteria

1. Epithelial invasive carcinoma of the breast with distant metastatic disease (M1)
2. Age = 18 years
3. First diagnosis of metastatic disease or disease progression (before start of new treatment regimen)
4. Written informed consent

Exclusion Criteria

Secondary primary malignancy (except in situ carcinoma of the cervix or adequately treated basal cell carcinoma of the skin)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of HER2 positive CTCs with each method

Secondary Outcome Measures

Name	Time	Method
Concordance between the two methods in (HER2 positive) CTC detection