Study of B cell functions in multiple sclerosis.
Recruiting
- Conditions
- multiple sclerosis, B cells
- Registration Number
- NL-OMON24833
- Lead Sponsor
- no sponsor, study performed by Hasselt University (Belgium), Agoralaan gebouw D, 3590 Diepenbeek, Belgium
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 160
Inclusion Criteria
Blood samples (10-15ml) are collected from healthy individuals, multiple sclerosis (MS) patients and neurologic control patients. Cerebrospinal fluid (5-10ml) is obtained via lumbar puncture from MS patients and neurologic controls. The lumbar puncture and blood puncture is done in order to get a correct diagnosis. In this way, trouble and risk for the patient is minimal. During this routine puncture, an extra volume is taken for this study. When the diagnosis is different from MS, the patient will be included in the control population. We aim to include 10 patients with a clinically isolated syndrome, 130 MS patients, 80 control patients and 80 healthy controls.
Exclusion Criteria
N/A
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method