To study the effect of postoperative pain following breast surgery using local anaesthestic infiltratio
Phase 3
- Conditions
- Health Condition 1: null- breast cancer
- Registration Number
- CTRI/2017/08/009401
- Lead Sponsor
- Monisha B J Neelankavil
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
breast cancer patients undergoing modified radical mastectomy
Exclusion Criteria
Known hypersensitivity or contraindication to Bupivacaine or Dexmedetomidine; pregnancy, drug allergy, cardiac patients, renal patients, significant pulmonary diseases, bleeding diathesis, psychological, neurological, metabolic diseases,Chronic analgesic drug abuse (on oral analgesics for more than a month).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)To compare the postoperative analgesic effects of bupivacaine following mastectomy <br/ ><br>2)To compare the postoperative analgesic effects of dexmedetomidine following mastectomy <br/ ><br>3)To compare the postoperative analgesic effect of Bupivacaine combined with Dexmedetomidine following mastectomy. <br/ ><br>4)To compare the requirement of analgesics following mastectomy between the two groups for 24 hours <br/ ><br>Timepoint: visual analogue score of more than 5
- Secondary Outcome Measures
Name Time Method 1)To compare the postoperative analgesic effects of bupivacaine following mastectomy <br/ ><br>2)To compare the postoperative analgesic effects of dexmedetomidine following mastectomy <br/ ><br>3)To compare the postoperative analgesic effect of Bupivacaine combined with Dexmedetomidine following mastectomy. <br/ ><br>4)To compare the requirement of analgesics following mastectomy between the two groups for 24 hours <br/ ><br>Timepoint: ramsay sedation scale of 2 or 3 <br/ ><br>modified aldrete score more than 9