Study on the Recovery of Visual Perceptual Function Dysfunction in Patients With Diabetes

Not Applicable

Completed

• Conditions: Diabetic Retinopathy (DR); Visual Perception

• Registration Number: NCT07095777
• Lead Sponsor: The First Affiliated Hospital of Anhui Medical University

Brief Summary

Investigators aim to investigate the effectiveness of visual perceptual learning on visual perceptual function in participants with diabetic retinopathy and to provide novel therapeutic insights for visual functional rehabilitation in diabetic retinopathy.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-03-01
• Primary Completion: 2024-07-31
• Study Completion: 2024-08-09
• Status Verified: 2025-07
• Study First Submitted: 2025-07-16
• Study First Submitted QC: 2025-07-23
• Last Update Submitted: 2025-07-23
• Study First Posted: 2025-07-31
• Last Update Posted: 2025-07-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• moderate to severe non-proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy(PDR) prior to treatment(17)
• prior pan retinal laser photocoagulation (PRP) at least 4 weeks before enrollment or vitreoretinal surgery at least 8 weeks before enrollment
• stable clinical condition
• best-corrected visual acuity (BCVA) > 1.0 logMAR (equivalent to a Snellen visual acuity of < 20/200)
• clear refractive media
• age ≤ 65 years
• ability to comprehend the examination and training procedures

Exclusion Criteria

• significant refractive media opacity
• psychiatric disorders, chronic alcoholism and traumatic brain injury
• new-onset vitreous hemorrhage, myopia, strabismus, amblyopia, glaucoma and macular diseases.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
contrast sensitivity	From enrollment to the end of treatment at 12 weeks	The contrast sensitivity measurements include grating acuity, first-order motion stimulus perception sensitivity, second-order stationary stimulus perception sensitivity and second-order motion stimulus perception sensitivity, which represent the reciprocal of the contrast threshold.

Secondary Outcome Measures

Name	Time	Method
The Low Vision Quality of Life Questionnaire	From enrollment to the end of treatment at 12 weeks	This instrument has demonstrated high reliability and validity, and is sensitive to changes in visual function among individuals with vision loss. The minimum value is 25 and the maximum value is 125. Higher scores indicate better quality of life.

Trial Locations

Locations (1)

The First Affiliated Hospital of Anhui Medical University; 🇨🇳 Hefei, Anhui, China