Minder hinder na een epileptische aanval
Recruiting
- Conditions
- EpilepsyElectroconvulsive therapyPostictal stateAcetaminophenNimodipineHypoperfusionEpilepsieElektroconvulsietherapiePostictale faseParacetamolNimodipineHypoperfusie
- Registration Number
- NL-OMON26656
- Lead Sponsor
- niversity of Twente, Enschede; Rijnstate Hospital, Arnhem
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 33
Inclusion Criteria
Adulthood (age > 17 years);
Current clinical diagnosis of depressive episode (unipolar, bipolar, schizoaffective);
Exclusion Criteria
Known adverse reactions to acetaminophen or nimodipine. In that case participants can still be included into the other intervention groups;
Chronic use of acetaminophen, calcium-antagonists or NSAID’s that cannot be interrupted for less than two days before the ECT-session.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome measure will be ‘time to EEG normalization’, defined as the time interval between seizure onset and return to the pre-ECT (baseline) EEG, quantified with the temporal Brain Symmetry Index. This is a well-defined, robust and generally accepted quantitative metric of EEG background evolution over time.
- Secondary Outcome Measures
Name Time Method