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Physiological Responses in Tobacco Chippers

Completed
Conditions
Smoking
Stress
Registration Number
NCT01237834
Lead Sponsor
Oregon Health and Science University
Brief Summary

This study will analyze a series of biological and behavioral markers in different populations of smokers. The study groups will differ in their cigarette consumption and level of nicotine dependence. This analysis will help to identify factors that might be important for smoking behavior and nicotine addiction. The results from this study will contribute to improve campaigns for smoking prevention and treatments for smoking cessation.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
178
Inclusion Criteria
  • healthy adults
  • age 25-55
Exclusion Criteria
  • alcohol or drug addiction
  • unstable significant medical problems
  • neurologic disease
  • medications known to affect CNS function or impact physiologic parameters measured in the study
  • significant visual impairment
  • breath carbon monoxide (BCO) level of less than 10 ppm for smokers
  • breath carbon monoxide (BCO) level of more than 5 ppm for non-smokers
  • for heavy regular smokers: erratic smoking history (i.e. they must have smoked an average of 15 cigarettes daily for at least one year)

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
ElectroencephalographyChanges from baseline during a hard cognitive task

Electroencephalography will be measured during performance on a hard cognitive task.

Secondary Outcome Measures
NameTimeMethod
Salivary cortisolChanges from baseline during performance on a hard cognitive task

Salivary cortisol will be measured at baseline, during a hard cognitive task and 30 minutes after the cognitive task.

Trial Locations

Locations (1)

Oregon Health and Science University

🇺🇸

Portland, Oregon, United States

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