Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia After Arthroscopic Anterior Cruciate Ligament Reconstruction (ACL)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 51
- 试验地点
- 1
- 主要终点
- tramadol consumption
研究概览
简要总结
arthroscopically Anterior Cruciate Ligament Reconstruction (ACL) under spinal anesthesia were included in this study.
详细描述
Patients who American Society of Anesthesiologists (ASA) classification I to II scheduled to undergo arthroscopically assisted ACL reconstructions under spinal anesthesia are included in this study. The first group is administered 150 mg oral pregabalin 1 hour before surgery and the postoperative sham block was performed with an ultrasound probe. The second group is the control group; patients in this group are administered a placebo capsule 1 hour before surgery and sham block was performed with an ultrasound probe.The third group is administered a placebo capsule 1 hour before surgery and postoperative adductor canal block is performed. All patients will be received postoperative a tramadol i.v. patient control analgesia device. At the end of 24 hours, the total amount of tramadol consumed by the patient will be recorded from the patient control analgesia. NRS score, white fast track, satisfaction will be questioned.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients between the ages of 18 and 70 years
- •American Society of Anesthesiologists I or II
- •Scheduled to undergo knee arthroscopy
排除标准
- •allergic to any medicines
- •History of drug or alcohol abuse,
- •Opioids or sedative medications
- •History of psychiatric conditions
- •Pregnant or lactating women
研究组 & 干预措施
pregabalin (lyrica)
pregabalin (lyrica) 150 mg preoperative 1 hour before and the postoperative sham block will perform.
干预措施: pregabalin (lyrica) (Drug)
placebo group
a placebo capsule 1 hour before surgery and the postoperative sham block will perform.
干预措施: Placebo oral tablet (Drug)
adductor channel block group
A preoperative placebo capsule will be given.This group will receive postoperative adductor channel block including 10 mL of 0.25% bupivacaine with 5 μg/mL epinephrine
干预措施: adductor canal block including bupivacaine (Drug)
结局指标
主要结局
tramadol consumption
时间窗: 24 hours
24 hours tramadol consumption will be recorded as milligrams
11-point numerical rating scale (NRS)
时间窗: 24 hours
11-point numerical rating scale for pain (0='no pain' and 10='worst pain possible pain') were explained.
次要结局
未报告次要终点
研究者
Fatma Kavak Akelma
specialist doctor
Ankara Diskapi Training and Research Hospital
