NCT04797546WithdrawnPhase 1
Impact of Adductor Canal Block, Compared to Patient Controlled Analgesia, in the Surgical Stress Response of Patients Programmed for Traumatic Anterior Cruciate Ligament Repair
Conditions
Trial Snapshot
- Phase
- Phase 1
- Status
- Withdrawn
- Locations
- 1
- Primary Endpoint
- Change of Blood Cortisol from baseline to 24 hours
Study Overview
Brief Summary
To evaluate the surgical stress response in anterior cruciate ligament repair with an adductor canal block versus patient controlled endovenous analgesia.
Detailed Description
Preoperative, 2 hours and 24 hours stress biomarkers will be evaluated in two groups of patients, continous adductor canal block and morphine patient controlled endovenous analgesia.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •18-65 years,
- •traumatic Anterior Cruciate Ligament tear, scheduled for elective arthroscopic repair with Semitendinous-Gracillis technique at first time in the morning, with full articular range,
- •no other traumatologic lesions.
Exclusion Criteria
- •denied consent to participate,
- •chronic steroids user,
- •diabetes type 1 or 2,
- •insulin resistance,
- •concurrent infectious disease,
- •cognitive failure, coagulopathy,
- •allergy to study drugs,
- •surgery scheduled in the afternoon
Outcomes
Primary Outcomes
Change of Blood Cortisol from baseline to 24 hours
Time Frame: 24 hours
Blood Cortisol will be evaluated preoperatively, 2 hours and 24 hours postoperatively.
Secondary Outcomes
- Change of Glycemia from baseline to 24 hours(24 hours)
- Change of C Reactive Protein from baseline to 24 hours(24 hours)
Investigators
Study Sites (1)
Loading locations...
Similar Trials
Completed
Phase 2
ACB Versus IA Analgesia in Knee ArthroscopyPostoperative PainNCT04715152Assiut University72
Unknown
Not Applicable
Comparing Adductor Canal Block and Adductor Canal Block-Local Infiltration Analgesia for Post-operative Pain ManagementACL TearACLACL InjuryNCT04721119Ottawa Hospital Research Institute100
Completed
Not Applicable
Efficacy of Adductor Canal Block for Anterior Cruciate Ligament SurgeryAnterior Cruciate Ligament InjuriesNCT05532618St. Antonius Hospital34
Recruiting
Not Applicable
Geniculate Nerve Block Versus Adductor Canal Block for ACL Reconstruction SurgeryACL TearPain, PostoperativeNCT06486246Hospital Clinic of Barcelona40
Completed
Not Applicable
Peri-articular Injection and (IPACK) With Adductor Canal Block in Total Knee Arthroplasty.Postoperative PainRegional AnesthesiaNCT04396652Tanta University60