Skip to main content
Clinical Trials/NCT04721119
NCT04721119
Unknown
Not Applicable

Comparison of the Effectiveness of Adductor Canal Block Versus Combination of Adductor Canal Block and Local Infiltration Analgesia: A Randomized Controlled Trial of the Effect on Postoperative Analgesia and Motor Power

Ottawa Hospital Research Institute0 sites100 target enrollmentFebruary 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
ACL Tear
Sponsor
Ottawa Hospital Research Institute
Enrollment
100
Primary Endpoint
Oral morphine equivalent consumption
Last Updated
5 years ago

Overview

Brief Summary

Anterior cruciate ligament (ACL) reconstruction is one of the most commonly performed surgeries amongst young orthopedic surgery patients. Optimal post-operative pain control helps to reduce the opioid burden and to improve the patient's experience. Regional anesthesia, such as the femoral nerve block (FNB) and adductor canal block (ACB), are commonly used for post-operative pain control after surgery. The ACB has replaced the FNB. This is because the ACB targets the femoral nerve, while avoiding the numbing effects on quadricep muscle strength that make it difficult to move the leg. Another form of pain control is local infiltration anesthesia (LIA), which directly blocks pain in the knee. Similar to the ACB, it avoids the numbing effects on the quadricep muscle.This can help improve patient safety and experience by reducing risks of falls and allowing the patient to move earlier. This can also be associated with decreased time in the hospital and decreased costs. Technically, it is less complex and can be done the shorter period of time.

The purpose of this study is to refine the pain management technique following anterior cruciate ligament surgery. More specifically, the aim of this study is to evaluate the effects of LIA alone, and a LIA-ACB combination on post-operative pain and thigh muscle strength.

Registry
clinicaltrials.gov
Start Date
February 2021
End Date
November 2021
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • English speaking or any other language with possibility of adequate translation
  • ASA I-III patients
  • Age 18-50
  • BMI ≤ 38 kg/m2

Exclusion Criteria

  • Refusal or inability to provide informed consent
  • Any contraindication to regional anesthesia including coagulopathy or bleeding diathesis,
  • Allergy to local anesthetics, or infection at the site of the block
  • History of long-term opioid intake (more than 3 months use) or chronic pain disorder (more than 3 months)
  • History of preexisting neuropathy in the operative leg
  • Revision of ACL repair

Outcomes

Primary Outcomes

Oral morphine equivalent consumption

Time Frame: Up to 24-hours after surgery

Cumulative oral morphine equivalent consumption over 24 hours post-op

Quadriceps motor strength

Time Frame: Pre-op, 30 minutes post-anesthesia

Percent decrease in quadriceps motor strength at 30 minutes following anesthesia compared to baseline

Secondary Outcomes

  • inta-operative opioid consumption(during surgery)
  • Time in hospital(From hospital admission to hospital discharge (approximately 12 hours))
  • Nerve Block Complications(up to 24 hours post-operative, up to 2 weeks post-operative)
  • Post-operative Pain(Up to 24 hours post-operative)
  • Quality of Recovery(At 24 hours post-operative)
  • Oral morphine equivalent consumption in PACU(PACU admission to PACU discharge (approximately 4 hours))

Similar Trials