Comparison of Two Types of Exercise Training for Asthmatic Subjects : Interests and Limits
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 2
- 试验地点
- 4
- 主要终点
- Maximal oxygen consumption (VO2max)
研究概览
简要总结
The aim of the study is to compare two methods of exercise training: alternate load versus constant load realized at moderate or high intensities, in order to define the interests and the limits of each one of these two methods. The finality is to make possible to the expert to choose what exercise training induces the best results quickly and to make its choice according to the therapeutic objectives which it lays down.We also evaluate the effects of these exercises training on the vagal response and the bronchial tone of the asthmatics. From a clinical point of view, a close attention will be paid to the effects of these exercises training on the control of asthma and the quality of life of the subjects
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 to 45 years old
- •mild to moderate persistent asthma (GINA classification)
- •stabilized asthma
- •physical activity level between 5 and 11 (Baecke and coll, 1982)
- •no contra-indication for physical training
排除标准
- •cardiovascular pathology
- •metabolic pathology
- •traumatic pathology
结局指标
主要结局
Maximal oxygen consumption (VO2max)
时间窗: At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training
Maximal power output (Pmax)
时间窗: At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training
次要结局
- Exhaled NO (eNO)(At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training)
- Heart rate variability(At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training)
- Force Expiratory Volume in one second (FEV1)(At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training)