Effect of probiotic in premenstrual syndrome
- Conditions
- premenstrual syndrome.
- Registration Number
- IRCT20180425039412N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 160
Age range 18-40 years
BMI Between 35 and 25
Affection of premenstrual syndrome based on PSST questionnaire
The normal duration of bleeding (3-7 days in the 3 months before entering the study) and the regular monthly cycle
Lack of chronic systemic diseases and diseases related to the ovary
Lack of liver disease, bile duct disease, gastrointestinal and intestinal diseases, kidney disease, parathyroid thyroid and non-hyperphosphatemia
Non-use of probiotic and probiotic-based supplements over the past 6 months
Not using supplements containing vitamins and minerals supplement W3 or fish oil
Non-development of neurological diseases and no use of psychosomatic drugs
Non-use of hormonal drugs
The desire to participate in the study and written consent written consent
Absence of iron deficiency anemia
Non-use of steroidal and non-steroidal anti-inflammatory drugs, Anti epileptic drugs, anti cholesterolemic drugs, anti-acid drugs, diuretics and laxatives
Not using any medication or dietary supplement that affects weight
Consumption of probiotic supplementation from 3 months before study
Affection of acute and chronic diseases of depression
Iron deficiency anemia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depression. Timepoint: Before the intervention, 1.2 and 3 months after the intervention. Method of measurement: questionnaire.
- Secondary Outcome Measures
Name Time Method