Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in COPD

Not Applicable

Completed

• Conditions: Chronic Obstructive Pulmonary Disease
• Interventions: Behavioral: Pursed-lip breathing; Behavioral: Normal Breathing

• Registration Number: NCT01173328
• Lead Sponsor: Universidade Federal do Rio de Janeiro

Brief Summary

Pursed-lip breathing (PLB) has been advocated to reduce respiratory rate and improve oxygen saturation in patients with chronic obstructive pulmonary disease (COPD) at rest. Although PLB is a strategy that potentially reduces expiratory flow limitation, there are only few studies addressing its effects on exercise.

This study aimed to assess the ability of PLB to change the breathing pattern, degree of dynamic hyperinflation (DH) and arterial oxygenation in COPD patients during exercise. Exercise tolerance was evaluated by endurance time and respiratory mechanics was evaluated by forced oscillation technique.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-03
• Status Verified: 2008-08
• Primary Completion: 2009-10
• Study Completion: 2009-10
• Study First Submitted: 2010-07-19
• Study First Submitted QC: 2010-07-30
• Last Update Submitted: 2010-07-30
• Study First Posted: 2010-08-02
• Last Update Posted: 2010-08-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Clinical diagnosis of chronic obstructive pulmonary disease (COPD)
• Regular treatment at Clementino Fraga Filho University Hospital (UFRJ)

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Exclusion Criteria

• Exacerbation in the preceding 4 weeks
• SpO2<85% at peak exercise
• Other diseases that may contribute to dyspnea and exercise intolerance

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Pursed-lip Breathing	Pursed-lip breathing	-
Pursed-lip Breathing	Normal Breathing	-

Primary Outcome Measures

Name	Time	Method
Endurance time	within the first 01 hour

Secondary Outcome Measures

Name	Time	Method
inspiratory capacity	within the first 01 hour
oxygen saturation	within the first 01 hour
dyspnea	within the first 01 hour
forced oscillation variables	within the first 01 hour

Trial Locations

Locations (1)

Clementino Fraga Filho University Hospital; 🇧🇷 Rio de Janeiro, Brazil