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临床试验/NCT02424331
NCT02424331已完成不适用

Effect of Pursed Lips Breathing on Chest Wall, Mobility Diaphragmatic and Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease

Universidade Federal de Pernambuco1 个研究点 分布在 1 个国家目标入组 14 人开始时间: 2014年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
14
试验地点
1
主要终点
Chest wall (Analysis of lung volumes)

研究概览

简要总结

This study aimed to evaluate the acute effect of PLB technique on diaphragmatic mobility, the kinematics of the thoracoabdominal complex analysis of lung volumes and exercise tolerance in patients with Chronic Obstructive Pulmonary Disease (COPD). This is a study randomized cross-over clinical trial and blind, in subjects with Chronic Obstructive Pulmonary Disease (COPD) according to criteria of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) (FEV1 / FVC <0.7 and FEV1 <80% predicted) selected at the Clinical Hospital of the Federal University of Pernambuco (UFPE) and Otavio de Freitas General Hospital (HGOF). The investigators recruited 13 patients COPD (according to previous sample calculation) aged between 40 and 80 years, of both sexes. The first day was held evaluation of lung function, respiratory muscle strength, body composition, dyspnea index and functional capacity. On the second day was held evaluation of thoracoabdominal complex kinematics by plethysmography Optoelectronics (OEP) with Quiet Breathing (QB) or pursed-lips breathing (PLB). Lung volumes with 2 minutes with QB and 6 minutes PLB or only 6 minutes by QB as randomization were observed. Before and after performing the requested breathing pattern diaphragmatic mobility was observed by Ultrasonography (US) and requested the patient an Inspiratory Capacity maneuver (IC). The evaluator who performed the ultrasound was blinded as to the beginning of the breathing pattern of order performed by the patient.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Supportive Care
盲法
Double (Participant, Investigator)

入排标准

年龄范围
40 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • COPD diagnosis with stage II-IV (GOLD),
  • Stable clinical condition (no exacerbation or hospital admission in the last four weeks preceding the study)
  • Absence of other disease that may potentially contribute to dyspnea (heart disease, congestive heart failure, neuromuscular diseases, severe postural changes)

排除标准

  • BMI> 30 kg / m2
  • Musculoskeletal limitations
  • Use of oxygen therapy
  • Extreme discomfort during the procedure application

结局指标

主要结局

Chest wall (Analysis of lung volumes)

时间窗: One day during eight minutes

(L) by plethysmography optoelectronics.

Mobility diaphragmatic (mobility diaphragmatic (mm) by Ultrassonography)

时间窗: One day, before and after eight minutes of pursed lips breathing

Analysis of mobility diaphragmatic (mm) by Ultrassonography.

Exercise tolerance (Glittre AVD-Test)

时间窗: One day, for six minutes approximately. The test will be repeated after 20 minutes of rest.

Analysis by Glittre AVD-Test (capacity functional test) observing the test execution time (s).

次要结局

  • Dyspnea (Borg and MRC Scale)(One day, before and after implementation of Glittre-ADL Test)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Marcely Kellyane Florenço Barros

Master

Universidade Federal de Pernambuco

研究点 (1)

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