Effect of Pursed Lips Breathing on Chest Wall, Mobility Diaphragmatic and Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease

Not Applicable

Completed

• Conditions: Chronic Obstructive Pulmonary Disease
• Interventions: Other: Pursed Lips Breathing; Other: Quiet Breathing

• Registration Number: NCT02424331
• Lead Sponsor: Universidade Federal de Pernambuco

Brief Summary

This study aimed to evaluate the acute effect of PLB technique on diaphragmatic mobility, the kinematics of the thoracoabdominal complex analysis of lung volumes and exercise tolerance in patients with Chronic Obstructive Pulmonary Disease (COPD). This is a study randomized cross-over clinical trial and blind, in subjects with Chronic Obstructive Pulmonary Disease (COPD) according to criteria of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) (FEV1 / FVC \<0.7 and FEV1 \<80% predicted) selected at the Clinical Hospital of the Federal University of Pernambuco (UFPE) and Otavio de Freitas General Hospital (HGOF). The investigators recruited 13 patients COPD (according to previous sample calculation) aged between 40 and 80 years, of both sexes. The first day was held evaluation of lung function, respiratory muscle strength, body composition, dyspnea index and functional capacity. On the second day was held evaluation of thoracoabdominal complex kinematics by plethysmography Optoelectronics (OEP) with Quiet Breathing (QB) or pursed-lips breathing (PLB). Lung volumes with 2 minutes with QB and 6 minutes PLB or only 6 minutes by QB as randomization were observed. Before and after performing the requested breathing pattern diaphragmatic mobility was observed by Ultrasonography (US) and requested the patient an Inspiratory Capacity maneuver (IC). The evaluator who performed the ultrasound was blinded as to the beginning of the breathing pattern of order performed by the patient.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-03
• Primary Completion: 2015-01
• Study Completion: 2015-03
• Study First Submitted: 2015-03-05
• Status Verified: 2015-04
• Study First Submitted QC: 2015-04-22
• Last Update Submitted: 2015-04-22
• Study First Posted: 2015-04-23
• Last Update Posted: 2015-04-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• COPD diagnosis with stage II-IV (GOLD),
• Stable clinical condition (no exacerbation or hospital admission in the last four weeks preceding the study)
• Absence of other disease that may potentially contribute to dyspnea (heart disease, congestive heart failure, neuromuscular diseases, severe postural changes)

Exclusion Criteria

• BMI> 30 kg / m2
• Musculoskeletal limitations
• Use of oxygen therapy
• Extreme discomfort during the procedure application

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Quiet Breathing or Pursed Lips Breathing	Pursed Lips Breathing	Free or natural breathing for six minutes.
Quiet Breathing or Pursed Lips Breathing	Quiet Breathing	Free or natural breathing for six minutes.

Primary Outcome Measures

Name	Time	Method
Chest wall (Analysis of lung volumes)	One day during eight minutes	(L) by plethysmography optoelectronics.
Mobility diaphragmatic (mobility diaphragmatic (mm) by Ultrassonography)	One day, before and after eight minutes of pursed lips breathing	Analysis of mobility diaphragmatic (mm) by Ultrassonography.
Exercise tolerance (Glittre AVD-Test)	One day, for six minutes approximately. The test will be repeated after 20 minutes of rest.	Analysis by Glittre AVD-Test (capacity functional test) observing the test execution time (s).

Secondary Outcome Measures

Name	Time	Method
Dyspnea (Borg and MRC Scale)	One day, before and after implementation of Glittre-ADL Test	Assessed by Borg and MRC Scale (Medical Research Council).

Trial Locations

Locations (1)

Clinical Hospital; 🇧🇷 Recife, Pernambuco, Brazil