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临床试验/NCT06211517
NCT06211517招募中不适用

Subjective Experience of Psychotropic Drugs Among Adolescents (Their Parents and Professionals) With Anorexia Nervosa

Assistance Publique - Hôpitaux de Paris1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2024年5月20日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
90
试验地点
1
主要终点
Semi-structured interview

研究概览

简要总结

The purpose of this study is to access to the experiences of adolescents, their parents and healthcare professionals regarding psychotropic drugs in anorexia nervosa.

No preconceived ideas (according to qualitative methods) but a question: what are the participants' perceptions and experiences of psychotropic drugs in anorexia nervosa? In an adolescent medicine department.

详细描述

Psychotropic prescription is common to adolescents suffering from anorexia nervosa. A first qualitative study (E3A Protocol "Experience of adolescents with anorexia nervosa toward antidepressants") looked at the experience of antidepressants among 15 adolescents suffering from anorexia nervosa. Analysis of the interviews identified two meta-themes:

  1. Reactions to the proposal of antidepressant with an opposition phase (about the existence of depressive symptoms and about negative preconceptions) and need to share with family and other teenagers.
  2. Reactions to antidepressant use with ambivalence and an initial perception of coercion, and effects of antidepressants (psychological effects, effects on the body and on anorexia nervosa and effects perceived through the eyes of others).

Nine adolescents (out of 15) were also taking an atypical antipsychotic (APA) often prescribed in case of anorexia nervosa resistance.

The need to share with family about the proposal of antidepressant and the effects perceived through the eyes of others (including parent's eyes) lead us to take an interest in parents perceptions.

Two decisive periods were identified: What do healthcare professionals think about psychotropic treatments for anorexia nervosa in adolescence? How do they propose treatment?

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
12 Years 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adolescents :
  • Aged 12 to 25 years
  • Suffering from anorexia nervosa (restrictive or mixed) according to DSM-5 (Diagnostic and Statistical Manual) criteria
  • Received psychotropic drugs (antidepressant treatment and/or APA) during their care, either ongoing or discontinued before this study started
  • Parents of adolescents suffering from anorexia nervosa for whom a psychotropic drug has been prescribed and whose adolescents meet inclusion criteria
  • Healthcare Professionals working with adolescents suffering from eating disorders

排除标准

  • Adolescents :
  • Atypical eating disorder that does not meet the DSM-5 criteria for restrictive or mixed anorexia nervosa
  • Prescription of an antidepressant other than an SSRI (Selective Serotonin Reuptake Inhibitor)
  • Prescription of an APA for the indication of psychotic symptoms

结局指标

主要结局

Semi-structured interview

时间窗: Day of inclusion

Themes describing adolescent experiences regarding psychotropic drugs in anorexia nervosa - Emergence of themes describing participants' experience from analysis of qualitative interviews (with Interpretative Phenomenology Analysis methodology)

次要结局

  • Semi-structured interview(Day of inclusion)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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