A Scalp Lotion Toimprove Sensitive Scalp Syndrome
- Conditions
- AlopeciaSensitive Skin
- Registration Number
- NCT05630027
- Lead Sponsor
- Cosmetique Active International
- Brief Summary
Overall, 100 Caucasian subjects participated in this 6-weeks lasting study, AC5+ was applied daily. All subjects had clinically confirmed mild to moderate alopecia and self-declared sensitive scalp. Instrumental assessments included Trans Epidermal Water Loss (TEWL), inflammation markers, clinical assessments included the severity of erythema, inflammation and greasiness. Subjective/Self assessments comprised the intensity of the scalp itch/pruritus and the evaluation of their head hair status (volume, abundance, strength). Same assessments were provided by the investigators.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Not specified
- Target Recruitment
- 100
- >18 years
- mild alopecia:
- female: Ludwig type 1
- male: Hamilton III to IV type
- Moderate or severe alopecia
- Dandruff
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method erythema Day 21 on a scale from o=none to 5=severe
inflammation Day 21 on a scale from o=none to 5=severe
greasiness Day 21 on a scale from o=none to 5=severe
Global soothing score Day 21 sum of the symptoms with a score up to 15
- Secondary Outcome Measures
Name Time Method hair quality Day 21 on a scale from o=none to 5=severe
Squalene monohydroperoxide Day 21 skin swabs analysis
pruritus Day 21 on a scale from o=none to 5=severe
burning Day 21 on a scale from o=none to 5=severe
Inflammation markers Day 21 skin swabs analysis skin swabs analysis
stinging Day 21 on a scale from o=none to 5=severe
scratching Day 21 on a scale from o=none to 5=severe
Transepidermal water loss Day 21 instrumental measurements
squalene Day 21 skin swabs analysis skin swabs analysis
Trial Locations
- Locations (1)
L'OREAL Research and Innovation
🇫🇷Saint-Ouen, France