NCT04668911Unknown不适用
Oral Health, Microbial Burden and COVID-19
Eastman Dental Insitute and Hospital1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2020年12月13日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Oral microbial signature
研究概览
简要总结
An observational study of patients with COVID-19 confirmed cases (with various degrees of severity) and controls.
Oral and nasal swabs will be taken from 150 patients (50 with mild form and 50 with severe form of COVID-19 with or without mechanical ventilation, 50 healthy controls).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Must provide written informed consent
- •Subjects have to be tested (PCR) positive or negative for SARS-CoV2 infection
- •Must be able to provide oral and nasal swabbing within 48 hours of polymerise chain reaction (PCR) test results
排除标准
- •a. Under the age of 18 years old
结局指标
主要结局
Oral microbial signature
时间窗: Day 1
To assess the oral microbial signatures that relates to SARS-CoV2 in patients with no, mild and severe disease.
次要结局
- Nasal microbial signature(Day 1)
研究者
Prof Francesco D'Aiuto
Professor
University College, London
研究点 (1)
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