Clinical and microbiological efficacy of continuous versus intermittent application of meropenem in critically ill patients: a randomized prospective single center study

Charles University Teaching Hospital Plzen (Czech Republic)0 个研究点目标入组 240 人开始时间: 2012年1月20日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Patients aged 18 years and over
•2. Admitted to the interdisciplinary Intensive Care Unit (ICU) between September 2007 and May 2010
•3. Had suffered from severe infection and received meropenem with predicted duration of treatment for at least 4 days at the admission or during the ICU stay
•4. Types of infections include:
•4.1. Abdominal
•4.2. Respiratory
•4.3. Skin
•4.4. Soft tissue
•4.5. Bloodstream
•4.6. Central nervous system
•4.7. Urinary tract
•4.8. Other sources of infections

•1. Age younger than 18 years
•2. Pregnancy
•3. Acute or chronic renal failure with glomerular filtration rate lower than 0.5 ml/s
•4. Immunodeficiency or immunosuppressant medication
•5. Neutropenia
•6. Hypersensitivity or allergy to meropenem

发起方

Charles University Teaching Hospital Plzen (Czech Republic)