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The effect of gender on the 50% effective dose of remimazolam for achieving loss of consciousness

Not Applicable
Completed
Conditions
Not Applicable
Registration Number
KCT0007951
Lead Sponsor
Ajou University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
60
Inclusion Criteria

Adult patients aged 19-60 years with ASA score 1 or 2 scheduled for general anesthesia

Exclusion Criteria

BMI > 30 kg/m2
History of allergies to benzodiazepines
History of allergies to opioids
Patients unable to response on verbal command
Use of opioids, alcohol, benzodiazeplines and over-the-counter sleep aids

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Gender difference in 50% effective dose of remimazolam for achieving loss of consciousness with remifentanil target-controlled infusion
Secondary Outcome Measures
NameTimeMethod
ED50, ED95 acheived by isotonic regression, vital signs (blood pressure, heart rate, oxygen saturation), UniCon (ADMS™, Anaesthetic Depth Monitor for Sedation) index, loss of consciousness time
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