Influence of Gender on the Plasma-Effect site equilibration time of propofol anesthetic and Cisatracurium Besylate neuromuscular blocking agent. A pilot study. - Gender Anesthesia
- Conditions
- effect of Gender on Pharmacokinetics of Propofol and cisatracurium
- Registration Number
- EUCTR2009-017921-20-AT
- Lead Sponsor
- niv. Klinik für Anästhesiologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 20
Twenty consecutive male and twenty female, ASA I-II patients, aged 18-45 yr, undergoing general anaesthesia for scheduled elective urological or kidney surgery will be recruited in the study.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Potential participants with body mass index <20 or > 26 kg/m2, or patients on treatment with drugs thought to interfere with neuromuscular transmission (aminiglycosides antibiotics, antiarrhythmics, antiepileptics, anticonvulsant, diuretics, lithium and magnesium) or patients scheduled to receive propofol Total Intravenous Anesthesia (TIVA) will be excluded from the study.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: Pharmacokinetics gender differences in Propofol and cisatracurium;Secondary Objective: None;Primary end point(s): Pharmacokinetic parameters of cisatracurium and propofol
- Secondary Outcome Measures
Name Time Method