Effect of one injection during removal of tooth/teeth of upper jaw

Phase 1

Active, not recruiting

Conditions: Chronic apical periodontitis,

Registration Number: CTRI/2019/12/022334

Lead Sponsor: Dr Monalisa

Brief Summary: Pain associated with administration of injectable local anaesthesia has been subject of research from the time of advent of local anaesthetic agents.

Among the different injection techniques used, palatal anaesthesia is the most painful, and from a long time research has been directed at reducing the pain associated with intra oral palatal injections.

Different methods such as topical anesthetic application, topical cooling of palate, computerized injection systems, pressure administration, Eutectic mixture of local anaesthesia (EMLA) and Transcutaneous electronic nerve stimulation have been tried but still are in the process of getting universal acceptance.

The reason for the pain is attributable to adherence of palatal mucoperiosteum to the bone and lack of a subcutaneous tissue layer which leaves minimal space for deposition of the local anesthetic solution.

Recentreports have suggested that removal of a maxillary tooth was possible without use of palatal anaesthesia with Articaine Hydrochloride 4% as a local anesthetic agent.

However, other researchers have refuted these claims.

It still remains to be established whether Articaine alone is effective for use in maxilla during removal of maxillary teeth without any palatal injection.

The scope of current research is to compare and examine the effectiveness, safety and side effects of Lignocaine Hydrochloride 2% and Articaine Hydrochloride 4% in the extraction of maxillary posterior teeth with specific regard to avoidance of a palatal injection to establish palatal anesthesia.

The pharmacologic properties of Articaine, which is capable of diffusing greater distances than other local anesthetics, coupled with the uniformly thin, cancellous maxillary bone, provide a plausible explanation for the success of palatal anesthesia achieved through buccal infiltration of Articaine, obviating the need for a palatal injection.

Detailed Description: Not available

Recruitment & Eligibility

Status: Closed to Recruitment of Participants

Sex: All

Target Recruitment: 120

Inclusion Criteria

1.Age group- above 18 years 2. Physical status.
ASA I and ASA II 3. Maxillary posterior teeth without mobility or associated pathology.

Exclusion Criteria

Immunocompromised patients 2.
Physical status ASA III and above 3.
History of allergy to local anaesthetics 4.
Withdrawn consent 5.
Pregnant and Lactating Women 6.
Active Periodontitis.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
2.Procedure pain	10 min
3.Frequecy of requirement of palatal injection	10 min
1.Injection pain	10 min

Secondary Outcome Measures

Name	Time	Method
1.Number of analgesics used	2. Duration of anaesthesia

Trial Locations

Locations (1): school of dental sciences,sharda university
🇮🇳
Nagar, UTTAR PRADESH, India
school of dental sciences,sharda university
🇮🇳Nagar, UTTAR PRADESH, India
Dr Monalisa
Principal investigator
8867253243
drmonalisa93@gmail.com