Lean Seafood Intake and Postprandial Metabolism

Not Applicable

Completed

• Conditions: Metabolic Diseases; Glucose Metabolism Disorders; Hyperlipidemias; Nutritional and Metabolic Diseases; Nutrition Disorders
• Interventions: Dietary Supplement: Lean seafood; Dietary Supplement: Meat, egg, milk

• Registration Number: NCT01708681
• Lead Sponsor: National Institute of Nutrition and Seafood Research, Norway

Brief Summary

Despite numerous studies of meal components in humans, little is still known about how different meals influence on metabolism. The purpose of this study is to a gain knowledge of how a balanced test meal with either lean seafood (example:cod) or meat as the main protein source will:

1. affect the postprandial metabolism acutely (test-meal at beginning of the study)

2. affect the postprandial metabolism after 4 weeks controlled intervention (test meal at end of intervention period)

3. affect gut microbiota composition

Detailed Description

Not available

Study Timeline

• Study Start: 2012-10
• Study First Submitted: 2012-10-11
• Study First Submitted QC: 2012-10-15
• Study First Posted: 2012-10-17
• Primary Completion: 2013-05
• Study Completion: 2015-09
• Status Verified: 2015-10
• Last Update Submitted: 2015-10-05
• Last Update Posted: 2015-10-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

• 18-65 years of age
• Caucasian

Exclusion Criteria

• Smoking
• Diabetes
• Hysterectomy
• Abnormal bleeding last 6 months
• Use of medication that affects lipid and glucose metabolism
• Large (>10%) alteration in body-weight the last 6 months
• Chronic, metabolic or acute disease or major surgery within last 3 months
• Dietary incompatibility with calcium supplementation and/ or seafood consumption (allergy, intolerance, dislike)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Meat, egg, milk	Lean seafood	Cross-over design, half of the subject will receive meat, egg, milk in study period I and the other half in study period II
Lean seafood	Lean seafood	Cross-over design, half of the subject will receive lean seafood in study period I and the other half in study period II
Lean seafood	Meat, egg, milk	Cross-over design, half of the subject will receive lean seafood in study period I and the other half in study period II
Meat, egg, milk	Meat, egg, milk	Cross-over design, half of the subject will receive meat, egg, milk in study period I and the other half in study period II

Primary Outcome Measures

Name	Time	Method
Postprandial lipid measurement	Change from baseline at 4 weeks

Secondary Outcome Measures

Name	Time	Method
Postprandial glucose measurement	Change from baseline at 4 weeks

Trial Locations

Locations (1)

National Institute of Nutrition and Seafood Research; 🇳🇴 Bergen, Norway