Comparison of Desipramine – Serteraline – Venlafaxine in Major Depression Disorder of Patients with Alzheimer Disease
Phase 2
- Conditions
- Major Depression.Severe depressive episode without psychotic symptoms
- Registration Number
- IRCT201108165280N6
- Lead Sponsor
- Mashhad University of Medical Scinces
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
the patients or their family sign informed consent; Approving Mild To Moderate Alzheimer Disease Using Dsm?-TR Criteria By Psychiatrist; Out Patient Treatment; No Other Medication Except : H2 blockers – Anti Hypertensive Or Other Cardiovascular Drugs And Medications For Hypercholestrolemia. Exclusion Critera: Any Psychotropic Drugs (Except Achetyl – Aceterase Inhibitor ) During Last 2 Weeks; Substance Abuse; Any Other Psychiatric Illness; side effects of medication during study; the patient decided to leave the study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depression. Timepoint: weeks 2-4-8-12. Method of measurement: HRSD (Hamilton rating scale depression).
- Secondary Outcome Measures
Name Time Method Mental Status. Timepoint: weeks 0,2,4,8,12. Method of measurement: Minimal Mental Status Examination (MMSE).