A Study on Neurocognitive Functions as a Predictor of Functional Outcome in Patients with Schizophrenia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 76
- 试验地点
- 1
- 主要终点
- The current study would be helpful in understanding the effect of selected neuropsychological tools in predicting functional outcome in patients with schizophrenia. It would also help in portraying effect of clinical and socio-demographic factors as mediator and moderator variables respectively in predicting functional outcome in patients with schizophrenia, with neurocognitive functions serving as independent variable and functional outcome dependent variable.
研究概览
简要总结
Neuro-cognitive deficits constitute one of the core areas of deficits witnessed in patients with schizophrenia. Among neuro cognitive deficits, memory functions and executive functions are the two robust areas where impairments are noticed in this group of patients. Like cognitive deficits, functional deficits too are present in most patients with schizophrenia at the onset of illness and level of impairment is quite substantial. Different cognitive test batteries such as Measurement and treatment research to improve cognition in schizophrenia (MATRICS), Consensus Cognitive Battery (MCCBTM), Cogstate have been developed with the objectives of providing brief evaluations of key cognitive domains related to schizophrenia, to improve clinical research and care around the world. All of these batteries are based on western norms and have not been standardized on Indian population. The present study aims at exploring the predictive sensitivity of commonly used Indian neuropsychological tools for the assessment of prefrontal lobe and medial temporal lobe functions in predicting the functional outcome in patients with schizophrenia. Additionally, the study will also explore the role of clinical and socio-demographic factors in mediating and moderating the relationship respectively, between neuropsychological functioning and functional outcome.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 59.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients diagnosed with schizophrenia as per ICD 10 CDDG(F20.0-F20.9),visiting LGBRIMH from different localities of Assam, who provide informed consent to participate in the study ,with normal to corrected to normal vision.
排除标准
- •Patients with comorbid neurological illness as obtained through medical record file and who have not received ECT in past one month.
结局指标
主要结局
The current study would be helpful in understanding the effect of selected neuropsychological tools in predicting functional outcome in patients with schizophrenia. It would also help in portraying effect of clinical and socio-demographic factors as mediator and moderator variables respectively in predicting functional outcome in patients with schizophrenia, with neurocognitive functions serving as independent variable and functional outcome dependent variable.
时间窗: Baseline(01)
次要结局
- To develop cognitive remediation strategies for this group of patients, based on the obtained mediating and moderating factors(Baseline(01))