Study to Develop a Breath Analyser to Detect Chronic Kidney Disease
- Conditions
- Kidney Diseases
- Interventions
- Diagnostic Test: breath
- Registration Number
- NCT03303222
- Lead Sponsor
- University College, London
- Brief Summary
Measure trimethylamine oxide in the breath.
- Detailed Description
Organic compounds such as trimethylamine oxide (TMAO) accumulate in the blood of patients with kidney disease, and volatile compounds such as TMAO can be detected in the breath.
The investigators wish to develop a breath analyser to measure volatile compounds, such as TMAO in the breath in patients with kidney disease.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- patients with kidney disease under the care of Royal Free Hospital
Exclusion Criteria
- patients unable to provide informed consent
- patients unable to exhale into breath analyser
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description patients with chronic kidney disease breath patients with chronic kidney disease not treated by dialysis patients on dialysis breath patients with kidney disease treated by dialysis
- Primary Outcome Measures
Name Time Method measurement of breath TMAO 3 years measurement of breath TMAO by breath analyser
- Secondary Outcome Measures
Name Time Method