NCT00744159已完成不适用
Prospective Comparative Study of Immunological Benefit Between Laparoscopic Colectomy and Open Colectomy
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 84
- 试验地点
- 1
- 主要终点
- Immune factors
研究概览
简要总结
This study aimed to clarify existence of immunological benefit of laparoscopic colon cancer surgery compared to open colon surgery.
详细描述
Patients with clinical stage Ⅲ left colon and upper rectal cancer were prospectively assigned to undergo LC (n=35) or OC (n=39). Factors related to cellular immunity of host (total lymphocyte count, CD4 lymphocyte, CD8 lymphocyte, CD4/CD8 ratio, HLA-DR expression on monocyte (mHLA-DR)) were examined preoperatively, on the 1st day of operation (POD1) and the 5th day of operation (POD5).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Biopsy proven of colon cancer
- •Preoperatively suspected as clinical stage III colon cancer
- •Lesion located Descending colon, sigmoid colon and upper rectal cancer
排除标准
- •Could not perform curative resection
- •Intestinal obstruction, perforation, intra-abdominal abscess
- •Severe medical illness
- •Immunopathy
结局指标
主要结局
Immune factors
时间窗: post OP 5th day
次要结局
- Post-operative complications(POD 7th days)
研究者
研究点 (1)
Loading locations...
相似试验
撤回
不适用
Impact of Immunoscore Colon Test on Adjuvant Therapeutic Strategy in Non-Metastatic Colon CancerColonic NeoplasmsNCT03946033UNICANCER
已完成
4 期
Cytokines of Patients With Transversus Abdominis Plane Block After Laparoscopic Colonic SurgeryLaparoscopic Colonic SurgeryNCT02219542China Medical University, China80
招募中
不适用
The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on the Immune Function for Cirrhosis PatientsCirrhosis, LiverStatus SplenectomyNCT05338294Northern Jiangsu People's Hospital20
已完成
不适用
Comparison of Laparoscopic and Open Surgery for Colorectal Malignancy in Obese PatientsObesityColorectal CancerNCT06221878Chang Gung Memorial Hospital473
已完成
不适用
Prospective Randomized Trial Comparing Endoscopic Submucosal Dissection Against Laparoscopic Assisted Gastrectomy for Treatment of Early Gastric CancerEarly Gastric CancerNCT03136354Chinese University of Hong Kong36