Cytokines of Patients With Transversus Abdominis Plane Block After Laparoscopic Colonic Surgery

Phase 4

Completed

• Conditions: Laparoscopic Colonic Surgery
• Interventions: Drug: transversus abdominis plane block

• Registration Number: NCT02219542
• Lead Sponsor: China Medical University, China

Brief Summary

The investigators designed a study to determine whether with combined general-transversus abdominis plane block anesthesia or standard general anaesthetic would provide same level of cytokines in patients undergoing Laparoscopic Colonic Surgery.

Detailed Description

The investigators designed a study to determine whether combined general-transversus abdominis plane block anesthesia or standard general anaesthetic would provide same level of cytokine in patients undergoing Laparoscopic Colonic Surgery.

Study Timeline

• Status Verified: 2014-05
• Study Start: 2014-08
• Study First Submitted: 2014-08-14
• Study First Submitted QC: 2014-08-15
• Study First Posted: 2014-08-19
• Primary Completion: 2015-02
• Study Completion: 2015-02
• Last Update Submitted: 2015-06-30
• Last Update Posted: 2015-07-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• •Participants were deemed eligible if they were candidates for spinal anesthesia undergoing Laparoscopic Colonic Surgery

Exclusion Criteria

• •Existing cognitive impairment as evidenced by Mini-Mental State Examination scores below 24 (of the 30 possible points)

  • A history of neurological and psychiatric diseases including stroke, and psychosis
  • Severe visual or hearing impairment
  • Unwillingness to comply with the protocol or procedures

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
a standard general anesthesia	transversus abdominis plane block	a standard general anesthesia and with transversus abdominis plane block 20 ml 0.9% sodium chloride
transversus abdominis plane block	transversus abdominis plane block	a standard general anesthesia with transversus abdominis plane block 20 mL 0.25% ropivacaine

Primary Outcome Measures

Name	Time	Method
The change of cytokine level in plasma samples	just after anesthesia induction ; at the end of the surgery; 24h after surgery	The blood samples were collected before induction of anesthesia and at the end of surgery.

Trial Locations

Locations (1)

the First Hospital of China Medical University; 🇨🇳 Shenyang, Liaoning, China