Efficacy of a Microalgae Extract PhaeoSOL Combined With Natural Stimulant on Cognitive Function and Gaming Performance of Video Gamers

Not Applicable

Completed

• Conditions: Video Gamers; Cognitive Function
• Interventions: Dietary Supplement: Phaeosol low dose; Dietary Supplement: Phaeosol high dose; Dietary Supplement: Placebo

• Registration Number: NCT04851899
• Lead Sponsor: Microphyt

Brief Summary

Considering the important growing development of gaming in the world, this research area has developed considerably over the last few years. Even if it seems to be well admitted that video gamers showed better cognitive functions (e.g. visual selective attention, cognitive flexibility, task switching) parameters compared to non video gamers there is a constant concern for optimizing performance as for all other kind of athletes. However to our knowledge, only one randomized controlled trial have investigated the potential benefits of dietary supplementation on cognitive function and performance in video gamers. The use of microalgea as molecule of interest sources is a recent promising approach also to meet societal challenge as the maintain of biodiversity/landscape.

Thus, the purpose of this study is to examine whether acute (single-dose) and chronic (1 month) supplementation of Microphyt's phaeosol ingredients (BrainPhyt) ingested with or without a natural stimulant, would affect cognitive function and gaming performance in experienced video gamers.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-04-15
• Study First Submitted QC: 2021-04-15
• Study First Posted: 2021-04-21
• Study Start: 2021-04-26
• Primary Completion: 2022-06-01
• Study Completion: 2022-06-01
• Status Verified: 2022-09
• Last Update Submitted: 2022-09-22
• Last Update Posted: 2022-09-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Healthy men and women;
2. Between 18 and 40 years;
3. Self-reported history of playing video games for 5 or more hours per week for 6 months prior to screening;
4. BMI between 18 and 34.9 Kg/m2 ;
5. Subjects agreed to supply their own operator-oriented action or strategy video game that they had played at least 21 times over the last 3 months;
6. No recent ingestion (<2weeks) of dietary supplement that affect cognitive function;
7. Be able to give written informed consent and to consume the investigational product daily for the duration of the study;
8. Is free-living (living in a private home, alone or with family, and able to maintain their health and hygiene without assistance)
9. Willing to maintain consistent sleep duration the evening before study visits.
10. Are agreed to continue their patterned use of the game between study visits

Exclusion Criteria

1. refrain from caffeine and alcohol for 12 hours prior to each study visits;
2. consume dietary supplements that may affect cognition and/or with a stimulant effect (e.g. guarana, cocoa, ginseng, bacopa, Gingko biloba, guayusa, yerba mate, energy drinks, other products containing fucoxanthin) at least 7 days before Visit 2 ;
3. are women who are pregnant, breastfeeding, or wish to become pregnant during the study;
4. have an untreated psychotic or major depressive disorder or any history of cognitive deficit;
5. have an uncontrolled hypertension/diabetes/thyroid/heart disease disease, cancer etc.);
6. have a significant neurological disease;
7. have planned major changes in lifestyle (i.e. diet, dieting, exercise level, travelling) during the duration of the study;
8. have a history within previous 12 months of alcohol or substance abuse;
9. have known allergy to any of the ingredients in the supplement product
10. are not willing to supply their own gaming system and/or game

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Low dose Phaeosol group	Phaeosol low dose	1 Phaeosol softgel of 440mg/day and 1 placebo softgel of 440mg/day look like softgel of Phaeosol product) + 1 capsule of 440mg/day of natural stimulant
High dose Phaeosol group	Phaeosol high dose	2 Phaeosol softgels of 440mg/day + 1 capsule of 440mg/day of natural stimulant
Placebo group	Placebo	2 placebo softgels of 440mg/day (look like softgel of Phaeosol product) + 1 capsule of 440mg/day containing Microcellulose (look like capsule of natural stimulant)

Primary Outcome Measures

Name	Time	Method
General attention	From week 0 to week 4	Change in general attention score - Go no go task test
Sustained attention	From week 0 to week 4	Change in sustained attention score - Psychomotor vigilance task test
Reaction time	From week 0 to week 4	Change in reaction time - Light tracking test
Attention shifting	From week 0 to week 4	Change in attention shifting score - Berg-Washington card sorting task test

Secondary Outcome Measures

Name	Time	Method
Mood state	From week 0 to week 4	Change in Mood state questionnaire score from 0 to 100 - Higher scores mean a better outcome - Profil of Mood state questionnaire
Global fatigue	From week 0 to week 4	Change in global fatigue score - Visual analogic scale from 0 to 100 - higher scores mean a worse outcome
Gaming performance	From week 0 to week 4	Change in gaming performance score from 0 to 100 - Higher scores mean a better outcome
Sleep quality	From week 0 to week 4	Change in sleep quality questionnaire score from 0 to 100 - Higher scores mean a better outcome
Eyes irritability	From week 0 to week 4	Change in eyes irritability score -Visual analogic scale from 0 to 100 - Higher scores mean a worse outcome

Trial Locations

Locations (1)

Exercise & Sport Nutrition Lab; 🇺🇸 College Station, Texas, United States