Investigation of the Effect of Exercise Protocol Determined According to Metabolic Rate in Early Burn Patients on Coagulation, Fibrinolytic Activity and Functional Capacity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 25
- 试验地点
- 2
- 主要终点
- MRC scale ( Manaul muscle test)
研究概览
简要总结
The aim of this study is; To investigate the Effect of the Exercise Protocol Determined According to Metabolic Rate in Early Burn Patients on Coagulation, Fibrinolytic Activity and Functional Capacity, and to create an exercise protocol that can guide researchers working in burn patients and physiotherapists working in burn centers at national and international level.
The study, which is planned to be carried out in Hasan Kalyoncu University Faculty of Health Sciences Department of Physiotherapy and Rehabilitation, will be included in the burn patients in the 25 Aralık State Hospital Burn Center, service and intensive care unit.
详细描述
Burn injury is one of the longest traumas, causing serious mortality and morbidity, and the length of hospital stay and rehabilitation period.
For optimal treatment after burns, all pathophysiological changes that may occur locally and systemically after injury should be well known.
Along with surgical and medical treatments, the role of early exercise in burn treatment is becoming more and more important.
Burn patients need a long rehabilitation period, including the acute period and the post-discharge period.
Early exercise is very important, especially in burn intensive care units, for healing of burns and minimizing the effects of hypermetabolism. Exercises should be started from the first day the patient is hospitalized.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Conscious patients Enterally fed >18 years old
排除标准
- •With inhalation burn
- •In addition to existing burn trauma, those with other trauma (fracture, loss of limb, etc.)
- •Organ dysfunctions or multiple organ failure
- •History of chronic diseases such as diabetes, cholesterol and blood pressure
结局指标
主要结局
MRC scale ( Manaul muscle test)
时间窗: Each participant will be evaluated for 6 weeks.
Peripheral muscle strength of the upper and lower extremities will be measured manually with the Medical Research Council (MRC) scale and the Modified Medical Research Council 4-point scale (MMRC). Shoulder abduction, elbow flexion and wrist extension of the upper extremity; If it belongs to the lower extremity, hip flexion, knee extension and ankle dorsi flexion will be measured in the in-bed high sitting position as a modified position specific to intensive care. Grading according to the MRC scale is between 0-5 for each muscle group: the total MRC score is between 0-60, and values below 48 indicate muscle weakness.
fibrinogen (to measure changes in both coagulation and fibrinolytic activity)
时间窗: Each participant will be evaluated for 6 weeks.
blood test
D-dimer (To measure coagulation changes and Fibrinolytic Activity)
时间窗: Each participant will be evaluated for 6 weeks.
blood test
6 min walking test
时间窗: Each participant will be evaluated for 6 weeks.
The test involves asking the patient to walk the longest distance possible in a set interval of 6 min, through a walking course (corridor) preferably 30-m long. healthy subjects, the 6-min walk distance(6MWD) ranges from 400 to 700 m
prothrombin time
时间窗: Each participant will be evaluated for 6 weeks.
blood test
platelets (to measure changes in both coagulation and fibrinolytic activity)
时间窗: Each participant will be evaluated for 6 weeks.
blood test
physiological consumption index
时间窗: Each participant will be evaluated for 6 weeks.
Physiological consumption index (PCI) was calculated ((walking heart rate) - (resting heart rate)) / (walking speed)\]. 1
次要结局
未报告次要终点
研究者
Murat Ali ÇINAR
Resarch Asistant, Physical Therapist
Hasan Kalyoncu University