Comparison of two methods heparin infusion, intermittent intravenous injection and continuous infusion in patients with Acute Coronary Syndrome Disease
- Conditions
- Acute coronary syndrome.acute ischemic heart diseases
- Registration Number
- IRCT20170822035849N4
- Lead Sponsor
- Sabzevar University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
1. Patients with acute coronary syndrome according to the cardiologist's diagnosis
2- Conscious and informed consent of patients to participate in the study.
3-Being age in the range of 50 to 75 years
1. History of bleeding ulcers, especially in the gastrointestinal tract
2. The presence of active bleeding accompanied by discoloration of the blood, or a tendency to bleeding like hemophilia, thrombocytopenia, blood cancers
4. Suspicious cases of intracranial bleeding
4.The presence of suspected cases of intracranial hemorrhage
5. Suppurative thrombophlebitis
6. Wounded injuries or the massive loss of skin
7. Subacute endocarditis
8.The presence of renal failure
9. High blood pressure 160 /90 and resistant to treatment
10. Recent eye surgery or spinal cord
11. Higher rang of INR (more than 3.5 )and a platelet below 100,000
12. Having an APTT of more than 100
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Activated Partial Thromboplastin Time. Timepoint: By starting heparin injection, sampling has done at every 6 hours, which in 48 hours we have 8 samples for each of patients. Method of measurement: The first, blood sample is taken from the patient, and then poured into an APTT tube and transferred to the lab for testing.
- Secondary Outcome Measures
Name Time Method Platelets. Timepoint: Before starting heparin in both ways. Method of measurement: Blood platelets measurement.;The Bleeding. Timepoint: At least every 6 hours as well as if needed. Method of measurement: The measuring instrument are tests, clinical examination and biographies.