Metabolic Effects of High-amylose Wheat-based Rusks.
Not Applicable
Completed
- Conditions
- Hyperglycemia
- Interventions
- Other: Test meal
- Registration Number
- NCT02702934
- Lead Sponsor
- Federico II University
- Brief Summary
Amylose-amylopectin ratio may influence the rate of starch digestion. This randomized controlled study evaluated the postprandial metabolic effects of amylose-rich- wheat- based rusks in overweight subjects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
- Overweight/obese;
- 30-60 years.
Exclusion Criteria
- age <30 and >60 years;
- fasting triglycerides ≥400 mg/dl;
- fasting cholesterol >270 mg/dl;
- cardiovascular events (myocardial infarction or stroke) during the 6 months prior to the study;
- established diabetes mellitus or any chronic disease;
- renal and liver failure (creatinine >1.7 mg/dl and transaminases >2 times than normal values, respectively);
- anaemia (Hb <12 g /dl);
- any chronic disease.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Control rusks Test meal Test meal with 100g of carbohydrates coming from regular rusks used as control High-amylose rusks Test meal Test meal with 100g of carbohydrates coming from high-amylose rusks
- Primary Outcome Measures
Name Time Method Blood glucose 4 hours Incremental area under the curve
- Secondary Outcome Measures
Name Time Method Blood insulin 4 hours Incremental area under the curve
Intestinal fermentation 4 hours Incremental area under the curve
Blood triglycerides 4 hours Incremental area under the curve
Trial Locations
- Locations (1)
Department of Clinical Medicine and Surgery
🇮🇹Naples, Italy