Effects of Liquid Zinc Supplementation and Dispersible Zinc Tablets on Plasma Zinc Concentration
Not Applicable
Completed
- Conditions
- Zinc Deficiency
- Registration Number
- NCT00944853
- Lead Sponsor
- University of California, Davis
- Brief Summary
The study aims to compare the effects of two different formulations of zinc supplements on plasma zinc concentrations among young Burkinabe children.
- Detailed Description
1) To investigate the effects of short-term zinc supplementation, provided either as a dispersible tablet containing zinc sulfate ("ZinCfant," Nutriset Ltd; Malaunay, France) or as a liquid ZnSO4 solution, on changes in serum zinc concentration, compared with a placebo in young Burkinabe children; and 2) to assess the relationship between change in serum zinc concentration and the presence of altered intestinal permeability within each treatment group.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 462
Inclusion Criteria
- currently breast feeding
- informed consent of a parent or guardian.
Exclusion Criteria
- symptomatic acute or chronic febrile infections
- diarrhea within the past week
- consuming vitamin or mineral supplements or zinc-fortified infant formulas
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Plasma zinc concentration 3 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Toussiana Health District
🇧🇫Toussiana, Burkina Faso
Toussiana Health District🇧🇫Toussiana, Burkina Faso